Which hemodynamic parameter indicates a decrease in left ventricular filling during inspiration?

A leftward shift of the interventricular septum (IVS) during inspiration is indicative of a decrease in left ventricular filling. This phenomenon occurs primarily due to changes in intrathoracic pressure and the effects of respiration on cardiac hemodynamics. During inspiration, intrathoracic pressure becomes more negative, which can lead to an increase in venous return to the right heart. This shift subsequently affects the septum, tilting it toward the left side and potentially reducing left ventricular filling.

In this context, a leftward shift of the IVS during inspiration reflects the physical dynamics of the heart responding to respiratory changes, indicating that there is a temporary decrease in blood returning to or filling the left ventricle, which can impact overall cardiac output. Understanding this physiological response is crucial for assessing cardiac function and hemodynamics in various clinical scenarios.