In which area of the heart is angiosarcoma most commonly located?

Angiosarcoma is a rare and aggressive tumor that arises from the blood vessel lining, and it most commonly occurs in the right atrium and right ventricle of the heart. This preference for the right side of the heart is thought to be due to the hemodynamic factors present in that area, as well as the fact that the right atrium receives blood from the systemic circulation, which may increase the likelihood of tumor development.

The right atrium and ventricle are more accommodating for larger masses due to their larger size compared to the left heart chambers, thus angiosarcomas can grow and cause significant obstruction or invasion into surrounding structures. These tumors can lead to symptoms like pericardial effusion, arrhythmias, or heart failure due to their aggressive nature and location.

In contrast, though the left atrium, right ventricle, and left ventricle can host various types of cardiac tumors, they do not exhibit the same frequency as angiosarcoma when it comes to locations. The left atrium, while a site for other types of tumors such as myxomas, tends not to host angiosarcomas prominently, and the left ventricle is also less commonly the site for this